Windows 10: mxmetamux

I Accidentally turned of my windows defender real-time protection and i didn't notice that i downloaded a malicious malware file and now i can't open windows security because it keeps crashing. I downloaded an app named spyware5 and this is the file that recognized as a malware but everytime i open appdata it doesn't appear and if i go to the location of the file it keeps popping up access denied. PLEASE HELP

:)