Windows 10: Blue Screen saying: INACCESSIBLE_BOOT_DEVICE after trying to turn on Memory Integrity

HelloI have problem after trying turn Memory Integrity on, after restarting labtop getting Blue Screen saying: INACCESSIBLE_BOOT_DEVICEmy labtop:ThinkPad X1 Extreme 2nd

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unable to turn on memory integrity

unable to turn on memory integrity and it suggests a incompatible driver but no driver is listed as incompatible

 

Memory Integrity Won't Turn On

Thanks for your reply.

I've joined the Windows Insider Programme and updated my laptop to 22H2 as this appeared to be the only thing listed that I didn't currently have. It's installed, but when I tried to switch on Memory Integrity from the settings it still scans for incompatible drivers, doesn't seem to find any and then says it needs to restart. And again once I press restart it gets to the Medion logo (just before the windows screen appears) but just hangs there.

On the suggestion you've linked above, Option 2 is "Refresh or Reinstall Windows Defender". Now if I follow this step and delete the Windows Defender folder in the registry as suggested, do I need to reinstall or will Windows do this automatically when I restart? I don't want to go deleting the folder and then finding that I've shot myself in the foot so to speak.

**Update**

I tried Option 2 and unfortunately this hasn't worked either, my laptop still hangs on the Medion logo without loading Windows after reset. I have to hold the power button to turn off and restart, then it loads Windows succesfully but still with Memory Integrity off.

Option 3 doesn't seem to be the problem as it's not detecting any incompatible drivers.

 

Blue Screen after trying to turn on Memory Integrity

I just updated to Windows 11 and when I try to turn on the "Memory Integrity" under Core Isolation in the security settings I get a blue screen after my computer restarts with an error that says "What Failed: ACPI.sys".

The computer restarts after that and the Memory Integrity option is still off. According to windows turning this on will make me less vulnerable which is good! Any help on this is appreciated!

Here is my system information :

OS Name Microsoft Windows 11 Pro

Version 10.0.22621 Build 22621

Other OS Description Not Available

OS Manufacturer Microsoft Corporation

System Type x64-based PC

Processor AMD Ryzen Threadripper 3960X 24-Core Processor, 3800 Mhz, 24 Core(s), 48 Logical Processor(s)

BIOS Version/Date American Megatrends Inc. P1.50, 2/6/2020

SMBIOS Version 3.2

Embedded Controller Version 255.255

BIOS Mode UEFI

BaseBoard Manufacturer ASRock

BaseBoard Product TRX40 Creator

BaseBoard Version

Platform Role Desktop

Secure Boot State Off

PCR7 Configuration Elevation Required to View

Windows Directory C:\WINDOWS

System Directory C:\WINDOWS\system32

Boot Device \Device\HarddiskVolume2

Locale United States

Hardware Abstraction Layer Version = "10.0.22621.819"

Time Zone Eastern Standard Time

Installed Physical Memory (RAM) 64.0 GB

Total Physical Memory 63.9 GB

Available Physical Memory 56.9 GB

Total Virtual Memory 73.4 GB

Available Virtual Memory 63.8 GB

Page File Space 9.50 GB

Page File C:\pagefile.sys

Kernel DMA Protection Off

Virtualization-based security Not enabled

Windows Defender Application Control policy Enforced

Windows Defender Application Control user mode policy Off

Device Encryption Support Elevation Required to View

Hyper-V - VM Monitor Mode Extensions Yes

Hyper-V - Second Level Address Translation Extensions Yes

Hyper-V - Virtualization Enabled in Firmware Yes

Hyper-V - Data Execution Protection Yes