Windows 10: how do i prevent ads popping up in lower right corner screen they block my screen use !

how do i prevent ads popping up in lower right corner screen they block my screen use !

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How do you prevent those pop ups on the lower right of the screen?

How do you prevent the pop ups on the lower right corner of the screen in Windows Live Mail?

 

Ads appearing on Desktop in lower right corner Windows 10

This is extremely frustrating. I have tried everything. Rkill, malware bytes, rouge killer, and probably many others. Nothing seems to work. There are these stupid ads that pop up on my desktop every so often in the lower right corner of the screen. I enclosed a screenshot. Sometimes the ads are different but always the same style of ad. What is this? How do I stop them?

I am on a dell laptop, windows 10 home edition, I use Firefox (not sure if that matters). I have emptied cookies and offline content multiple times, does nothing to stop it. I have literally tried everything I could think of except maybe casting a spell on it, which probably also wouldn't work. Please help.

 

lower right corner adds

Have you ever had a add pop up in lower right corner of screen and it blocks your work? Have you clicked on remove and it sends you to a site? Have you powered up pc , you go to password and a add pops up? I have add blocker but Microsoft adds can not
be blocked, can they? Last week that pop up said loading, I did not know what add was loading so I powered off pc, turns out that a update was loading and I canceled it. Have you done that? It is very confusing when a update and adds are from the same place
and put in the same place. Can anybody tell me how to get Microsoft to stop with adds? Where is windows defender?