Windows 10: Not running new .exe or .msi files

Discus and support Not running new .exe or .msi files in Windows 10 Support to solve the problem; Hi All, I have a problem with my windows 10 installation. It is Win10 Enterprise version 1809(17763.1339). The problem: I cannot run some .exe, .msi... Discussion in 'Windows 10 Support' started by Devizes2008, Aug 11, 2020.

  1. DEVIZES2008
    Devizes2008 Win User

    Not running new .exe or .msi files


    Hi All,

    I have a problem with my windows 10 installation. It is Win10 Enterprise version 1809(17763.1339).
    The problem: I cannot run some .exe, .msi and other weird behaviour.
    My local IT colleagues are no help as they have never seen this behaviour.
    I can run all previously installed applications like office and other non-office .exe, but it seems that all new .exe that I want to run just wont work. Double clicking does nothing, no message whatsoever. However, I can run them using the command line interface (CMD). Im a local Admin of my machine.
    .msi files however show this in CMD Access denied.
    My IT support says that if there was anything blocking .exe files it would have to be done via MacAfee and we even uninstalled it (to test that theory) with the same results, not running any new .exe or .msi files. Also, when I try to right click on a .reg file to edit or merge it does nothing.
    Any ideas of what I should check?

    :)
     
    Devizes2008, Aug 11, 2020
    #1
  2. ERIC BER
    Eric Ber Win User

    Can't run .exe file

    Hi Phil,

    There are several reasons why you are having issues running .exe files on your Windows 10 laptop. To assist you better, kindly answer the questions below:

    • Have you made any changes to your laptop prior to this issue?
    • What troubleshooting steps have you done so far?
    • What is the error message that you received when running .exe files?

    Regards.
     
    Eric Ber, Aug 11, 2020
    #2
  3. SACHIN VENKATESH
    Sachin Venkatesh Win User
    Can't run exe file

    Hello Mike,

    I realize the inconvenience you are facing in running the .exe file. We will help you.

    To assist you better, I suggest you to answer the below questions.

    • What application are you trying to install?
    • Are you getting any error message when you try to install the application?
    • From where did you download the application?
    Please post to us with ,ore information to help you better.
     
    Sachin Venkatesh, Aug 11, 2020
    #3
  4. ROBOTOVERLORD
    robotoverlord Win User

    Not running new .exe or .msi files

    Cannot run .exe files

    I rebooted my computer and it downloaded some updates. When it restarted, I could no longer run any .exe files. When I click on one, it asks me which program I would like to use to run it. Obviously, there are no programs on the list it offers me. The
    weirdest part is that some downloaded applications (like chrome, thankfully) still run. Any suggestions on how I can fix this or what happened?
     
    robotoverlord, Aug 11, 2020
    #4
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Not running new .exe or .msi files

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