Windows 10: New SSD has successfully cloned OS, but won't boot (Non-system disk)

Fully operational perfectly running OS and Programs on old SSD. Macrium showed successful cloning (verified) to new SSD. Removed old and installed new. Non-system disk error.
Used W10 ISO CD to get to repair mode. Repair failed.
Went to CMD prompt (still using ISO disc) and used diskpart. All volumes showed, but all letters wrong. Used diskpart to change all letters and remove letter from small Recovery volume. All letters showed as correct on new SSD (and on second SSD, which was not involved in this switch of new and old System+programs SSDs). Reset BIOS to boot from Disk 0 (new SSD). Boot attempt produced Non-system disk error.
Used ISO to get back to diskpart. All volumes showed wrong letters again (same ones). Tried again. Repeated startup attempt. Non-system disk error.
I thought this was going to be easy: Clone old System+data SSD to new SSD, swap out old for new, boot, and the system runs perfectly from the new SSD (which now has a new lease on life). WRONG.
Please offer suggestions (other than re-install old SSD and carry on until it fails). I love and depend on this forum.

Please take care in this dangerous period of our lives.
W10 1909

:)

 

Windows 10 deactivated on new cloned SSD

Well it would appear the issue was solved!

What I did was re-insert and boot the original SSD went into Settings

Selected Accounts

Clicked on Manage my Microsoft account, got a message stating the account needed to be updated

After that was done, I cloned the new SSD again

On the cloned SSD entered command prompt, used the slmgr with my product key command (was entered successfully)

Then used the slmgr /ato command...and voila, Windows was reactivated successfully!

So thank you all for the possible solutions you suggested. I will keep monitoring the system as time goes by.

 

cloning OS partition to new hardware

HDClone does a good job. Since you're cloning from a hard drive to an SSD, go through this list after you've booted Windows on the SSD:

Check the partition alignment
http://www.overclock.net/t/1226963/how-to-properly-re-align-your-ssd-hdd-partitions

Verify that TRIM is enabled
How to Enable/Check TRIM/AHCI in Windows 7 - The Corsair User Forums

Disable disk defragging
Disk Defragmenter Schedule- Turn On or Off - Windows 7 Help Forums

 

Issues booting from cloned ssd

I use a L440 Thinkpad with windows 10. Recently I decided to upgrade my laptop which have a regular HDD. So bought a 480GB Sandisk SSD, mounted that to a caddy. Then replaced my optical drive with that caddy. When I turned on my laptop the SSD showed up
in "disk management". Formatted it with GPT by following the instructions available online. Then cloned the disk using EaseUS Todo backup. Everything is cloned successfully. But unfortunately I cannot boot from the SSD. Even the SSD doesn't show up in the
boot order.

Following various internet forums tried disabling "Secure boot" and choosing "Legacy only" from BIOS. But nothing works. It is to be noted that both my HDD and SSD are connected. As per instructions I shutdown right after cloning the disk into SSD, but nothing.
Any help regarding how can I boot from SSD?